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Liu T, Sun W, Guo S, Yuan Z, Zhu M, Lu J, et al

classified PD into 6 stages based on the extent of Lewy body distribution, ranging from minimally affected brains to those with widespread involvement [181] (Table 4)

Common ideas include that ferroptotic stress inducing TAMs to repolarize from M2 type to M1 type [128, 208,209,210], inducing ferroptosis of Tregs to reduce negative immune effect [127], targeting system Xc- to alleviate cystine deprivation in TME mediated by myeloid-derived suppressor cells (MDSCs) to promote T cell survival [211] and so on

As the supreme law and decision making body in this country, it is highly imperative for members of the Parliament to engage in constructive policy and issue debate and discussions, to ensure accountability in government and to provide relevant oversight