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In a rat model of cerebral ischemia-induced neurological impairment, the co-administration of tissue plasminogen activator (tPA) with nanoliposomal Fasudil-Lip showed better neuroprotection, and prolonged therapeutic time window (TTW) and improved drug targeting (Fukuta et al., 2017)

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Let's break this down a bit further: Oxidative Stress : This refers to an imbalance between the production of free radicals (and other reactive species) and the body's ability to detoxify these harmful molecules or repair the resulting damage

Drug glucuronidation in clinical psychopharmacology