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[4] Patients should never adjust dosing of either medication without medical supervision and should report any concerning symptoms to their healthcare provider promptly

They reflect pharmacokinetic logic for research use under appropriate oversight

Heffernan, Jiang, Thorburn, and Ng reported in the American Journal of Physiology that oral administration of AOD9401 to ob/ob mice was associated with reduced body-weight gain, altered adipose lipogenic and lipolytic activity, and acute changes in energy expenditure, evidence that a growth-hormone C-terminal fragment could act after oral delivery in a rodent model [3]