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In recalculating expenditures for the benchmark year, CMS applies the calculation methodology applied in recalculating expenditures for the corresponding performance year in accordance with 425.674

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Here, we summarize the mechanisms and dynamics of DNA methylation alterations in neurological diseases, such as immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome, Rett syndrome (RTT), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Alzheimers disease (AD), Parkinsons disease (PD), Huntingtons disease (HD), fragile X syndrome (FXS), and epilepsy