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We also found a negative correlation between Escherichia-Shigella enrichment and the attenuated apoptotic pathways in PSO during functional enrichment analysis, suggesting that Escherichia-Shigella enrichment is involved in attenuated apoptotic pathways in PSO patients

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[PMID:25974072] Calabro KA, Harmon CM, Vali K

People with PANS are often very sensitive to psychiatric medications, and in my experience, the commonly used psychiatric medications frequently are not effective or have negative side effects