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In the early 1990s, researchers began focusing on the role the pineal gland plays in the aging process, specifically, its ability to modulate functions of the neuroendocrine and immune systems, which have been shown to decease with age

This aligns with natural cortisol rhythms and allows any mild side effects to resolve before sleep

For hair growth, the credible endpoints are well established standardized global photography assessed by blinded evaluators, and target-area hair counts and density measured by trichoscopy or phototrichogram at fixed scalp sites over a sufficient duration (typically 24 weeks or more, because the hair cycle is slow)

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