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The sensitivity of R 4 parameters ( k p4 ) with respect to model OCR output is in good accordance with the AIC/BIC analysis, confirming the need for the R 4 reaction, which is present in both the triad and the comproportionation models, but not in the reduced model

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Inflamm Res 66:947959 Trist BG, Hilton JB, Hare DJ, Crouch PJ, Double KL (2021) Superoxide dismutase 1 in health and disease: how a frontline antioxidant becomes neurotoxic