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This result indicates that the reduction in BTC cell viability could not be attributed to an increase in apoptosis

In this regard, GSTs that also possess glutathione peroxidase activities may play a crucial role in plant antioxidative defense by limiting the excessive spread of HR-associated cell death (Levine et al., 1994

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Under pathological conditions, long-term excessive stress can cause damage to the endoplasmic reticulum function, and endoplasmic reticulum stress activates the apoptosis pathway, which leads to nerve cell damage and even death (Xuan et al., 2020)